What Is Cardarine (GW501516)?

Cardarine, also known by its chemical designation GW501516, is a research compound classified as a PPARδ (peroxisome proliferator-activated receptor delta) agonist. Despite frequently being grouped with SARMs in research compound discussions, Cardarine is technically not a SARM — it does not bind to androgen receptors. Instead, it activates PPARδ pathways, which play a central role in fatty acid oxidation, energy metabolism, and mitochondrial biogenesis.

Originally developed through a collaboration between GlaxoSmithKline and Ligand Pharmaceuticals in the 1990s, Cardarine was studied for its potential in metabolic syndrome, obesity, and dyslipidemia research before development was discontinued in 2007 following preclinical findings. It remains widely used in research settings for its distinct metabolic mechanism of action.

All products are sold strictly for laboratory and research purposes only. Cardarine is not approved by the FDA for human consumption.

Cardarine Product Specifications

Why Researchers Choose Our Cardarine

Who Purchases Cardarine for Research?

Cardarine (GW501516) is purchased across a broad range of research contexts including:

• Metabolic researchers studying PPARδ activation and fatty acid oxidation
• University labs investigating mitochondrial biogenesis and energy metabolism
• Research teams studying dyslipidemia and cholesterol regulation models
• Endurance and exercise physiology researchers studying oxidative capacity
• Obesity and metabolic syndrome researchers investigating lipid metabolism
• Biohackers running documented biomarker and performance protocols

All purchases are for laboratory and research use only. Cardarine is not approved by the FDA for human consumption and is not sold as a dietary supplement.

How Our Cardarine Compares

Frequently Asked Questions — Cardarine (GW501516)

• Is Cardarine legal to buy in the US?

  Yes. Cardarine (GW501516) is legal to purchase in the United States for research purposes. It is not a scheduled controlled substance under the DEA Controlled Substances Act and is not classified as a SARM under any current or proposed legislation — Cardarine is a PPARδ agonist, a distinct compound class.

  However, Cardarine is not FDA-approved for human consumption, cannot be legally sold as a dietary supplement, and may not be marketed with health or performance claims. It must be purchased strictly for legitimate laboratory or scientific research use. Always verify the current regulatory status in your state before ordering.

• What is Cardarine used for in research?

  Cardarine is studied across several metabolic and exercise physiology research areas due to its role as a PPARδ agonist. Published and ongoing research covers:

  • Fatty acid oxidation and lipid metabolism pathway research
  • Mitochondrial biogenesis and cellular energy production studies
  • Metabolic syndrome, obesity, and dyslipidemia investigations
  • Endurance capacity and oxidative muscle fiber research
  • Cholesterol regulation and HDL/LDL ratio studies
  • Inflammatory pathway modulation via PPARδ receptor activation

  All research use must comply with applicable institutional and regulatory guidelines. Cardarine is not approved for any therapeutic application in humans.

• Is Cardarine the same as a SARM?

  No. Cardarine (GW501516) is not a SARM. It is frequently grouped with SARMs in research compound discussions due to similar retail channels and user communities, but the two compound classes work via entirely different mechanisms:

  • SARMs (such as RAD140 or Ostarine) bind selectively to androgen receptors in muscle and bone tissue.
  • Cardarine activates PPARδ (peroxisome proliferator-activated receptor delta) receptors, which regulate fat metabolism, energy expenditure, and mitochondrial activity.

  This distinction is important for researchers designing protocols. Cardarine does not interact with the hormonal or androgen receptor pathways that SARMs target, making it a mechanistically distinct compound for metabolic and endurance-related research.

• How do I verify the purity of your Cardarine?

  Every batch of Cardarine we stock has a corresponding Certificate of Analysis (COA) issued by an independent, US-accredited third-party laboratory. We do not use in-house testing or recycle documentation across batches.

  Each COA includes:

  • HPLC purity percentage confirming compound concentration
  • Mass spectrometry identity verification matching the correct molecular weight of GW501516
  • Batch lot number that matches the label on the bottle you receive
  • Laboratory name and contact information for independent verification

  COAs are available for download directly on the product page without requiring an account or prior purchase. If your bottle’s lot number does not match the posted COA, contact us immediately for resolution.

• How fast does Cardarine ship and what are the delivery options?

  Orders placed before 2pm EST on business days ship the same day. Orders placed after 2pm EST or on weekends ship the next available business day.

  • Standard shipping: 2–4 business days via USPS or UPS depending on destination
  • Express shipping: 1–2 business days, selectable at checkout
  • Overnight delivery: Available on request for qualifying orders

  All orders are shipped in plain, discreet packaging with no product labeling visible externally. A tracking number is emailed immediately upon dispatch. We ship to all 50 US states. International shipping is not currently available.

• What payment methods are accepted?

  We accept all major payment methods with no hidden fees or processing surcharges:

  • Credit and debit cards: Visa, Mastercard, American Express — zero surcharge
  • Cryptocurrency: Bitcoin, Ethereum, and other major coins accepted
  • eCheck: Bank transfer via eCheck with standard clearing time
  • Zelle and Venmo: Available for domestic US orders

  Unlike the majority of research compound vendors who add 5–10% surcharges to card transactions, we charge no additional fees on any payment method. The price shown at checkout is the final price.

• What is the shelf life and storage requirement for Cardarine?

  Cardarine solution and powder maintain stability under correct storage conditions:

  • Solution: Store at room temperature (15–25°C / 59–77°F), away from direct sunlight, heat sources, and humidity. Stable for up to 24 months under correct conditions. Refrigeration is not required and may cause precipitation in solution.
  • Powder: Store in a cool, dry location away from light and moisture. When kept in a sealed container away from humidity, powder form typically maintains stability for 24–36 months.

  Each bottle is labeled with a manufacturing date and expiry date. Do not use the compound after the expiry date printed on the label or stated on the COA.

• Can I buy Cardarine in bulk quantities?

  Yes. Bulk and wholesale pricing is available for research institutions, private laboratories, and verified researchers requiring quantities above standard catalog listings. Both solution and powder formats are available for bulk ordering.

  Volume discount tiers are applied automatically at checkout for qualifying order sizes. For institutional purchase orders, custom invoicing, or high-volume requirements, contact us directly via the enquiry form with the following details:

  • Required quantity and preferred format (solution or powder)
  • Intended research application or institutional affiliation
  • Preferred delivery timeline and location

  All bulk orders are subject to the same independent third-party verification standards and include full COA documentation for every batch supplied.