What Is LGD-4033 (Ligandrol)?

LGD-4033, commonly known as Ligandrol, is a research compound classified as a selective androgen receptor modulator (SARM). Originally developed by Ligand Pharmaceuticals and later licensed to Viking Therapeutics, LGD-4033 was designed to investigate potential applications in muscle wasting, osteoporosis, and age-related lean tissue loss. It binds with high affinity and selectivity to androgen receptors in muscle and bone tissue.

LGD-4033 is widely regarded as one of the most studied SARMs in clinical research. It has progressed further into human clinical trials than most other SARMs in its class, with Phase I and Phase II studies published in peer-reviewed literature. Its high anabolic potency at relatively low concentrations has made it a reference compound in androgen receptor modulation research.

All products are sold strictly for laboratory and research purposes only. LGD-4033 is not approved by the FDA for human consumption.

LGD-4033 Product Specifications

Why Researchers Choose Our LGD-4033

Who Purchases LGD-4033 for Research?

LGD-4033 (Ligandrol) is purchased across a broad range of research contexts including:

• Independent researchers studying selective androgen receptor binding profiles
• University and private labs investigating muscle wasting and sarcopenia models
• Bone health researchers studying androgen receptor activity in skeletal tissue
• Clinical researchers referencing Phase I and Phase II LGD-4033 trial data
• Researchers comparing LGD-4033 potency against other SARMs and testosterone
• Biohackers running documented biomarker and lean tissue protocol studies

All purchases are for laboratory and research use only. LGD-4033 is not approved by the FDA for human consumption and is not sold as a dietary supplement.

How Our LGD-4033 Compares

Frequently Asked Questions — LGD-4033 (Ligandrol)

• Is LGD-4033 legal to buy in the US?

  Yes. LGD-4033 (Ligandrol) is legal to purchase in the United States for research purposes. It is not currently a scheduled controlled substance under the DEA Controlled Substances Act. However, the SARMs Control Act has been introduced in Congress on multiple occasions and, if passed, would reclassify SARMs including LGD-4033 as Schedule III controlled substances alongside anabolic steroids.

  LGD-4033 is not FDA-approved for human consumption, is not legal to sell as a dietary supplement, and cannot be marketed with health or performance claims. It must be purchased strictly for legitimate laboratory or scientific research use. Always verify the current regulatory status in your state before ordering.

• What is LGD-4033 used for in research?

  LGD-4033 is one of the most clinically studied SARMs available, with published Phase I and Phase II human trial data. Research areas include:

  • Muscle wasting, cachexia, and sarcopenia models
  • Lean tissue preservation and anabolic activity in androgen-deficient states
  • Bone density and osteoporosis prevention studies
  • Selective androgen receptor binding profile and tissue selectivity research
  • Comparisons of anabolic potency between LGD-4033 and testosterone
  • Post-surgical and age-related muscle loss recovery research

  All research use must comply with applicable institutional and regulatory guidelines. LGD-4033 is not approved for any therapeutic application in humans.

• What is the difference between LGD-4033 solution and LGD-4033 powder?

  Both formats contain the same compound — LGD-4033 (Ligandrol) — at verified purity. The difference is in preparation and intended application:

  • Solution (10mg/ml in 50ml): Pre-measured liquid ready for immediate use in research protocols. No preparation required. Ideal for consistent dosing studies and standard administration schedules.
  • Powder (1g): Raw compound in lyophilized form. Suited for researchers who need to prepare custom concentrations, formulate capsules, or conduct gravimetric measurement studies.

  Both formats are independently tested and supplied with a batch-specific Certificate of Analysis confirming compound identity and purity percentage.

• How does LGD-4033 compare to other SARMs like RAD140 and Ostarine?

  LGD-4033, RAD140, and Ostarine (MK-2866) are all selective androgen receptor modulators but differ significantly in potency, selectivity, and research profile:

  • LGD-4033 (Ligandrol): Considered the most potent SARM by anabolic effect at low concentrations. Has the most human clinical trial data of any SARM. Higher suppression profile than Ostarine.
  • RAD140 (Testolone): Highest reported anabolic-to-androgenic ratio (~90:1) in preclinical models. Less human trial data than LGD-4033. Also studied for neuroprotection.
  • Ostarine (MK-2866): Mildest of the three. Most studied SARM overall with the longest research history. Lower suppression profile. Often used as a reference compound.

  The choice between compounds depends entirely on the specific research protocol and androgen receptor pathway being investigated.

• How do I verify the purity of your LGD-4033?

  Every batch of LGD-4033 we stock has a corresponding Certificate of Analysis (COA) issued by an independent, US-accredited third-party laboratory. We do not use in-house testing or recycle documentation across batches.

  Each COA includes:

  • HPLC purity percentage confirming compound concentration
  • Mass spectrometry identity verification matching the correct molecular weight of LGD-4033
  • Batch lot number that matches the label on the bottle you receive
  • Laboratory name and contact information for independent verification

  COAs are available for download directly on the product page without requiring an account or prior purchase. If your bottle’s lot number does not match the posted COA, contact us immediately for resolution.

• How fast does LGD-4033 ship and what are the delivery options?

  Orders placed before 2pm EST on business days ship the same day. Orders placed after 2pm EST or on weekends ship the next available business day.

  • Standard shipping: 2–4 business days via USPS or UPS depending on destination
  • Express shipping: 1–2 business days, selectable at checkout
  • Overnight delivery: Available on request for qualifying orders

  All orders are shipped in plain, discreet packaging with no product labeling visible externally. A tracking number is emailed immediately upon dispatch. We ship to all 50 US states. International shipping is not currently available.

• What payment methods are accepted?

  We accept all major payment methods with no hidden fees or processing surcharges:

  • Credit and debit cards: Visa, Mastercard, American Express — zero surcharge
  • Cryptocurrency: Bitcoin, Ethereum, and other major coins accepted
  • eCheck: Bank transfer via eCheck with standard clearing time
  • Zelle and Venmo: Available for domestic US orders

  Unlike the majority of research compound vendors who add 5–10% surcharges to card transactions, we charge no additional fees on any payment method. The price shown at checkout is the final price.

• Can I buy LGD-4033 in bulk quantities?

  Yes. Bulk and wholesale pricing is available for research institutions, private laboratories, and verified researchers requiring quantities above standard catalog listings. Both solution and powder formats are available for bulk ordering.

  Volume discount tiers are applied automatically at checkout for qualifying order sizes. For institutional purchase orders, custom invoicing, or high-volume requirements, contact us directly via the enquiry form with the following details:

  • Required quantity and preferred format (solution or powder)
  • Intended research application or institutional affiliation
  • Preferred delivery timeline and location

  All bulk orders are subject to the same independent third-party verification standards and include full COA documentation for every batch supplied.