Chemyo MK-677 Review 2026 — Ibutamoren 25mg/ml 50ml
Updated April 2026·10 min read·GH Secretagogue Research
Chemyo MK-677 is one of the most purchased Ibutamoren products on the market. In this review we cover the product specifications, composition, COA documentation, pricing, and how Chemyo’s MK-677 compares to alternatives — so researchers can make an informed sourcing decision.
Chemyo MK-677 — Quick Verdict 2026
25mg/ml — highest standard concentration50ml — 67% more than 30ml competitorsFTIR + HPLC independently testedBatch-specific COA downloadable4.94/5 from 230 verified reviewsUS manufactured and fulfilledFree shipping over $100 US7.95% credit card surcharge
What Is Chemyo MK-677?
Chemyo MK-677 is a liquid solution of Ibutamoren (MK-677) at 25mg/ml in a 50ml bottle. It is one of Chemyo’s flagship products and consistently among their highest-reviewed compounds. MK-677 — also known as Ibutamoren, MK-0677, and Nutrobal — is a non-peptide ghrelin receptor agonist and growth hormone secretagogue studied for its ability to stimulate GH and IGF-1 output via the ghrelin receptor pathway.
Unlike injectable GH peptides such as CJC-1295, Ipamorelin, or GHRP-6, Ibutamoren is orally bioavailable — one of very few GH secretagogues that does not require injection to be active. This property has made it one of the most researched GH secretagogue compounds available and one of the consistently highest-volume products across SARM and research compound vendors including Chemyo.
Chemyo MK-677 Product Specifications
| Compound | MK-677 (Ibutamoren) |
| Synonyms | MK-0677 · L-163,191 · Nutrobal · Ibutamoren |
| Application | Non-peptide ghrelin receptor agonist |
| Concentration | 25mg/ml (2.5%) |
| Volume | 50ml per bottle |
| Total Compound | 1,250mg per bottle |
| Composition | 5% ethanol · 92.5% deionized water · 2.5% MK-677 (≥99% purity) |
| CAS Number | 159752-10-0 |
| Molecular Formula | C27H36N4O5S |
| Molar Mass | 528.662 g/mol |
| Testing Method | FTIR (identity) + HPLC (purity + concentration) |
| Purity | ≥99% |
| Batch Coding | Yes — induction sealed, unique lot number |
| COA | Publicly downloadable on product page |
| Price (1 bottle) | $79.99 |
| Price (2 bottles) | $75.99/ea (5% off + free US shipping) |
| Price (3+ bottles) | $71.99/ea (10% off + free US shipping) |
| Storage | Cool, dry place — minimize open air exposure |
Chemyo MK-677 — Quality and Testing
Chemyo MK-677 — Category Ratings
Purity documentation
9.9
Testing transparency
9.8
Concentration accuracy
9.6
Value per milligram
8.8
Shipping speed
9.2
Customer reviews (230)
4.94
FTIR and HPLC testing
Chemyo’s MK-677 undergoes two stages of independent third-party testing. The raw MK-677 powder is first tested for identity using FTIR (Fourier Transform Infrared Spectroscopy) and for purity using HPLC before it enters the manufacturing process. After the finished solution is prepared, it is tested again for concentration using an HPLC assay to confirm the active ingredient is present at the stated 25mg/ml.
This two-stage approach is not standard in the research compound market. Most vendors test once — if at all. Testing at the powder stage and again at the finished solution stage means any formulation error during manufacturing is independently identified before the product ships.
Batch coding and COA access
Each bottle of Chemyo MK-677 is induction sealed and assigned a unique batch code. The batch code on your bottle corresponds directly to the Certificate of Analysis posted on the Chemyo product page. The current batch as of April 2026 is BA2183, with both FTIR/HPLC results and concentration test results publicly available for download without account registration.
The COA confirms compound identity by FTIR spectral match and lists the HPLC purity result. The concentration test report lists the assay result for the finished solution — confirming the 25mg/ml label claim within the ±10% precision tolerance standard for liquid solution testing.
Composition transparency
Chemyo discloses the full composition of their MK-677 solution: 5% ethanol, 92.5% deionized water, and 2.5% MK-677 at ≥99% purity. Full solvent disclosure is not universal in the research compound market. Knowing the exact vehicle composition allows researchers to plan for solvent compatibility in their specific protocols and confirm the formulation aligns with published MK-677 research methodology.
Chemyo MK-677 Pricing — Is It Worth It?
At $79.99 for a single 50ml bottle at 25mg/ml, Chemyo MK-677 delivers 1,250mg of Ibutamoren per purchase. To evaluate value correctly, the comparison must be made on a per-milligram basis rather than headline bottle price.
| Vendor | Volume | Concentration | Total mg | Price | $/mg |
|---|---|---|---|---|---|
| Chemyo | 50ml | 25mg/ml | 1,250mg | $79.99 | $0.064 |
| Typical competitor A | 30ml | 25mg/ml | 750mg | $59.99 | $0.080 |
| Typical competitor B | 30ml | 25mg/ml | 750mg | $64.99 | $0.087 |
| Chemyo (3-pack) | 50ml x3 | 25mg/ml | 3,750mg | $71.99/ea | $0.058 |
At $0.064 per milligram for a single bottle — and $0.058/mg on the 3-pack — Chemyo MK-677 is competitively priced relative to the industry when measured correctly. Vendors selling 30ml bottles at lower headline prices consistently cost more per milligram of active compound delivered.
Credit card note: Chemyo applies a 7.95% processing surcharge to card payments. On a $79.99 order this adds approximately $6.36. Paying by eCheck or cryptocurrency avoids this surcharge and cryptocurrency payments may attract an additional discount. Factor this into your per-milligram cost comparison if paying by card.
Chemyo MK-677 Reviews — What Buyers Say
Chemyo MK-677 currently holds a 4.94 out of 5 rating based on 230 verified buyer reviews — 93% of which are 5-star. The review profile is notably consistent. Recurring themes across reviews include fast dispatch and delivery, discreet packaging, and satisfaction with product quality as observed by solution clarity, consistency, and correspondence to stated specifications.
The small percentage of 4-star reviews most commonly cite price as the only point of friction — not quality or service. There are no 1-star or 2-star reviews in the published dataset, and 3-star reviews account for less than 1% of the total. For a product with 230 reviews that is an exceptionally clean rating distribution.
Chemyo MK-677 vs Alternatives
Researchers comparing Chemyo MK-677 against other available sources should evaluate across five dimensions: testing depth, concentration accuracy, volume per bottle, shipping speed, and total landed cost including payment surcharges.
| Factor | Chemyo MK-677 | Typical Alternative |
|---|---|---|
| Testing method | FTIR + HPLC (dual) ✓ | HPLC only (most) |
| COA type | Batch-specific, public ✓ | Generic or on request |
| Bottle volume | 50ml ✓ | 30ml standard |
| Concentration | 25mg/ml confirmed ✓ | 25mg/ml (often unverified) |
| Composition disclosed | Full solvent breakdown ✓ | Often not disclosed |
| Review volume | 230 verified reviews ✓ | Variable |
| Credit card fee | 7.95% surcharge | Varies — some zero fee |
| US shipping speed | 2–5 business days ✓ | Similar |
The two areas where alternatives can match or beat Chemyo MK-677 are the credit card surcharge (some competitors charge zero) and catalog breadth if peptides are also required alongside MK-677. For MK-677 specifically as an isolated purchase, Chemyo is the strongest combination of testing transparency, volume per bottle, and verified buyer confidence currently available in the market.
Looking for a Chemyo MK-677 alternative?
We stock research-grade MK-677 at 25mg/ml in 50ml — same format, HPLC + MS tested, zero credit card fees.
Who Should Buy Chemyo MK-677?
Chemyo MK-677 is the right choice for researchers who prioritize testing transparency and want the most documented and reviewed Ibutamoren solution currently available in liquid format. The combination of dual-method independent testing, full composition disclosure, induction-sealed batch coding, and 230 verified reviews with a 4.94 average rating gives Chemyo MK-677 the most auditable quality trail of any MK-677 product currently on the market.
It is particularly well suited to researchers who intend to run extended protocols — the 50ml format and 3-pack volume discount represent meaningful cost savings versus 30ml alternatives over a multi-month research timeline. Researchers paying by eCheck or crypto will receive the best price. Those paying by card should factor the 7.95% surcharge into their cost comparison.
Frequently Asked Questions — Chemyo MK-677
- Is Chemyo MK-677 legitimate? + Yes. Chemyo MK-677 is independently tested by a US-accredited third-party laboratory using both FTIR for identity verification and HPLC for purity and concentration confirmation. The batch-specific Certificate of Analysis is publicly available for download on the product page. With 230 verified reviews at a 4.94 average rating, it is one of the most reviewed MK-677 products available from any research compound vendor.
- What concentration is Chemyo MK-677? + Chemyo MK-677 is formulated at 25mg/ml in a 50ml bottle. This delivers 1,250mg of Ibutamoren total per bottle. The 25mg/ml concentration is independently confirmed by HPLC assay testing on every batch and documented on the publicly available Certificate of Analysis.
- What is in Chemyo MK-677 solution? + Chemyo discloses the full composition of their MK-677 solution: 5% ethanol, 92.5% deionized water, and 2.5% MK-677 at ≥99% purity. CAS number 159752-10-0. Molecular formula C27H36N4O5S. Molar mass 528.662 g/mol. The ethanol/water vehicle is standard for aqueous Ibutamoren solution research protocols.
- How much does Chemyo MK-677 cost? + A single 50ml bottle of Chemyo MK-677 at 25mg/ml is priced at $79.99. Two bottles are $75.99 each with free US shipping (5% off). Three or more bottles are $71.99 each with free US shipping (10% off). Note that a 7.95% credit card surcharge applies to card payments — eCheck and crypto payments avoid this surcharge.
- How fast does Chemyo ship MK-677? + Chemyo processes and ships orders within 24–48 hours of placement excluding weekends and public holidays. US domestic delivery is typically 2–5 business days via USPS, UPS, or FedEx. Free shipping applies on US orders over $100. All orders ship in discreet, plain packaging with no external product labeling and full tracking provided by email on dispatch.
- Is there a cheaper alternative to Chemyo MK-677? + On a per-milligram basis, Chemyo MK-677 at $0.064/mg is competitively priced against most alternatives when the 50ml vs 30ml volume difference is correctly factored in. Vendors appearing cheaper at headline price typically deliver significantly less compound per bottle. The 3-pack reduces cost to $0.058/mg. The credit card surcharge adds approximately 5% to effective cost for card payers — eCheck or crypto removes this. Researchers who want zero card surcharges with comparable quality standards may also consider our own MK-677 listing as an alternative.
Related Chemyo Products
External References
Chemyo MK-677 Review — Final Verdict
Chemyo MK-677 is the most documented and independently verified liquid Ibutamoren product currently available in the research compound market. Dual-method FTIR and HPLC testing, full composition disclosure, batch-specific publicly accessible COAs, induction-sealed packaging, and 230 verified reviews at 4.94/5 represent a quality and transparency standard that no other MK-677 vendor currently matches in its totality.
The single practical drawback — the 7.95% credit card surcharge — is mitigated by paying via eCheck or cryptocurrency, and has no bearing on product quality. For researchers sourcing MK-677 and prioritizing verified purity over headline price, Chemyo remains the default benchmark choice in 2026.
Research Use Only. All compounds referenced in this article are intended for laboratory research purposes only. They are not approved by the FDA for human consumption and are not dietary supplements. This article is for informational purposes only and does not constitute medical or purchasing advice.